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VIDAS® Troponin I Ultra, VIDAS® CK-MB and VIDAS® Myoglobin* are automated quantitative assays for the assessment of myocardial damage.
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The VIDAS® Acute Coronary Syndrome (ACS) panel offers three complementary tests for the assessment of myocardial injury1, 2. Performed on the instruments of the VIDAS® family, these assays are particularly suitable for emergency testing.
Cardiac Troponin I (cTnI) is the preferred biomarker of cardiac necrosis due to its specificity for myocardial tissue damage2. A rapid increase of cTnl levels (within 3 to 6 hours after the onset of chest pain) and the fact they remain elevated for 4 to 7 days5 give cTnI high diagnostic value for myocardial infarction.
The protein concentration of the MB isoenzyme of human creatine kinase (CK-MB) is recommended for the diagnosis of myocardial infarction when cardiac troponin assays are not available5. CK-MB also increases rapidly after infarction. Due to its shorter half-life, it can be used as a marker for re-infarction.
Myoglobin is one of the first markers of myocardial damage to be measured after the onset of myocardial infarction. For patients presenting within 6 hours of the onset of symptoms, it may be considered in addition to cardiac troponin for rule-out5.
Temporal profile of cardiac necrosis markers after acute myocardial infarction
(adapted from [6]).
Clinical performance of VIDAS® Troponin I Ultra for patients presenting with symptoms suggestive of ACS*:
Clinical Performance (using the 99th percentile cut-off: 0.01µg/L)3
Clinical Performance (using the 10%CV cut-off: 0.11µg/L)7
* Please consult our local subsidiary or representatives for the availability of these products in your country.
** Depending on local guidelines.
References:
VIDAS® Troponin I Ultra | VIDAS® CK-MB | VIDAS® Myoglobin | |
---|---|---|---|
Reference | 30448 | 30421 | 30446 |
Kit size | 60 tests | 30 tests | 30 tests |
Sample type | Serum, plasma (heparin) | Serum, plasma (heparin, EDTA) | Serum, plasma (heparin) |
Sample volume | 200 µL | 250 µL | 150 µL |
Calibration / Control Frequency | 28 days | 14 days | 14 days |
Time to result | 20 minutes | 30 minutes | 17 minutes |
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Troponin I Ultra
CK-MB
Myoglobin
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